Scientist II/Sr. Scientist I, Immunology

Salary Band: $150,000-$200,000

Location: South San Francisco, CA

Job Summary

We are seeking an immunologist with experience in autoimmune and inflammatory diseases (not I/O) who owns the biology. As a member of a highly integrated team of biologists, computational scientists and protein scientists, you will design, execute, and interpret the in vitro and ex vivo experiments that determine whether a target is tractable, whether a compound engages it in human cells, and whether that engagement produces the biology we intended.

You will work in project teams and tackle the questions that determine program progression: is the cellular phenotype on-target, does the mechanism hold up in disease-relevant human systems, and what do the assay data tell us about whether to advance a series. Our research is focused on small-molecule modulation of immune signaling pathways that drive pathogenic inflammation, with the aim of achieving the selectivity and durability that current immunosuppressive approaches have not delivered.

The portfolio spans early target validation through IND-enabling studies, so you will see biology carried from first cellular proof of mechanism through to a development candidate. This is a hands-on individual-contributor role on the Antares scientific track,