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Posted 1h ago•South San Francisco, CA

Principal Scientist, Peptide Chemistry

principalOn-site (South San Francisco)Salary undisclosed
Job Description

Who We Are:

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description: 

Calico is seeking a Principal Scientist, Peptide Chemistry to join our Drug Discovery organization and lead a team focused on peptide design, synthesis and engineering to support Calico’s research and drug development projects. This role will work closely with structural biologists, computational modeling scientists, medicinal chemists, DMPK and formulation scientists to investigate structure-activity relationships and drive compound optimization. Additionally, this position will have the unique opportunity to collaborate with our Computing Group on the in silico design and validation for protein binders. 

The successful candidate must be highly motivated, detail-oriented, work autonomousl

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