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Posted 1mo ago•San Francisco

(Senior / Principal) Scientist, Medicinal Chemistry

principalOn-site (San Francisco)Salary undisclosed
Required Skills
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Job Description

We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.

We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.

Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.

We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.

About the Role

You will lead medicinal-chemistry design and synthesis across Capable’s therapeutic programs, deciding which compounds to make and translating SAR and biological data into the next design cycle. You will remain hands-on from route selection through purification and characterization while owning the chemistry decisions that improve potency

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