(Senior / Principal) Scientist, RNA Therapeutics
We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.
We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.
Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.
We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.
About the Role
You will lead RNA-therapeutics programs from target biology and oligonucleotide design through chemistry selection, assay strategy, quality control, and in vivo validation. You will build coherent programs—not isolated sequences—by connecting mechanism, tissue, potency, durability, safety, and manufacturability to clear experimental decis
