Senior Director, Global Medical Affairs
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026.
Description of Role
The Senior Director, Global Medical Affairs, will serve as the Global Medical Affairs Lead for Centessa's lead orexin receptor 2 agonist program. This strategic leadership role is responsible for developing and executing the global medical strategy across the product lifecycle, with a primary focus on launch readiness, scientific leadership, evidence generation, external engagement, and cross-functional partnership.
The successful candidate will hav
