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Posted 3h ago•New York

Senior Computational and Experimental Scientist

SeniorOn-site (New York)Salary undisclosed
Required Skills
Python
Job Description

About the Role

Join a lean team at an early-stage AI-driven biotech company, working across computational protein design, experimental biology, and scientific software. You will help close the design-make-test-model loop, using experimental results to improve models and deliver more useful sequences.

What You'll Do

  • Refine discrete diffusion, protein language, and structure prediction models, including model architectures and constrained redesign workflows.

  • Operate and improve a scientific inference platform, and analyze user behavior, usage patterns, and churn.

  • Write, debug, and deploy protocols for liquid-handling robots and manage screening instrumentation.

  • Run BLI or SPR assays end-to-end, from assay design and sample preparation through kinetic fitting and quality control.

  • Diagnose experimental and computational failure modes, including mass transport, nonspecific binding, aggregation, and poor referencing.

  • Design sequences, synthesize or express them, measure kinetics, update models, and iterate on improved candidates.

  • Support scientific users and customer adoption with accurate, personalized outreach and an understanding of biot

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