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Posted 3d ago•San Francisco, California, United States

Co-founder & CTO, AI for predictable drug discovery and development

MiddleOn-site (San Francisco)Salary undisclosed
Required Skills
Next.jsLLMs
Job Description

We're building AI to predict clinical trial and drug development outcomes, and quantify how much confidence those predictions deserve.

We're looking for a technical co-founder to join our biology and commercial founders. As Co-founder & CTO you take a built, already-used platform and lead its development, the research programme that measures and improves its predictions, and the first technical team. The aim is to spin the company out of DSV over the coming months.

THE OPPORTUNITY

Drug development involves decisions about targets, treatment approaches, delivery and patient populations. Each decision depends on evidence that may not transfer well to the setting that matters: treating people. A treatment working in mice, for example, does not tell us how much confidence to place in its chances in humans.

Around nine in ten drugs entering clinical trials never reach approval. The causes run from efficacy to safety to commercial choice, and the claim here is narrower than blaming that number on translation: the field still lacks a systematic way to measure how far a given experimental result should carry into a specific therapeutic decision.

We want to measure how reliably different kinds of biological evidence predict human outcomes. Our approach is to link the evidence available when a decision was made, the judgement made from it, and what happened next. Those records become the data from which we can learn which evidence p

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