Principal Scientist, Machine Learning

ABOUT PIONEERING INTELLIGENCE
 
Pioneering Intelligence builds on Flagship Pioneering’s legacy of founding cutting-edge science and computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a portfolio of AI-first  companies. As part of Flagship’s integrated model of science, entrepreneurship, and capital, it transforms breakthrough ideas into  world-changing companies, elevating the AI advances happening across the ecosystem in human health, sustainability, and 
beyond. 

THE ROLE 

We are seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects that accelerate pharmaceutical R&D across the preclinical, translational, and clinical continuum, working closely with Pioneering Medicines (PM) and across Flagship’s platform companies as part of the company origination process. You will define and deliver pragmatic AI strategies and oversee method and platform development across omics, biomolecule design, multi-o, systems biology, and scientific literature mining, ensuring rigor in model development, benchmarking, scaling, and reporting. Throughout, you will use LLM-based agents and agentic workflows as the connective tissue that ties these methods into end-to-end pipelines scient