Flagship Pioneering, Inc. logo
Posted 3h ago•Cambridge, MA USA

(Senior) Scientist, Translational Biology

SeniorOn-site (Cambridge)Salary undisclosed
Job Description

Company Summary

FL106 Inc. is a privately held, early-stage biotechnology company focused on developing novel drug delivery modalities. FL106 is backed by Flagship Pioneering, which provides the strategic vision and resources to advance FL106 from platform validation to clinical impact.

Position Summary

We are seeking a highly motivated and experienced Scientist to join our research team. The ideal candidate will have deep expertise in flow cytometry, primary cell isolation and sorting, microscopy and imaging, and gene-silencing techniques (siRNA), with in vivo/in vitro mouse experience. This role will contribute to the design and execution of preclinical studies to advance therapeutic programs.

Key Responsibilities

  • Design, execute, and analyze complex in vitro / in vivo experiments to support research programs
  • Lead and perform multi-parameter flow cytometry assays, including panel design, optimization, and data interpretation
  • Perform and optimize primary cell isolation from tissues, including enzymatic and mechanical tissue dissociation, magnetic-activated cell sorting (MACS), and fluorescence-activated cell sorting (FACS), with attention to preserving cell viability, yield, native gene-expression signatures, and potential for further

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