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Posted 5mo agoSan Diego HQ

Principal Scientist, Medicinal Chemistry

principalOn-site (San Diego)Salary undisclosed
Job Description

JOB SUMMARY

We seek an experienced and creative medicinal chemist with a proven track record of success in drug discovery. Candidates should be motivated to work in an intensely collaborative, multidisciplinary, team-based setting. The ideal candidate will be passionate about solving medicinal chemistry challenges, as well as proactively interfacing with diverse teams working on automated experimentation, AI-driven molecular generation, property predictions, and bioassay data generation.

This position is on-site at our San Diego Headquarters.

KEY RESPONSIBILITIES

  • Devise strategies to identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles.

  • Execute on high quality ideas by employing a broad range of modern organic chemistry transformations, synthetic methods, creative use of parallel experimentations and implementing innovative techniques.

  • Work closely with molecular and cellular biology, pharmacology, computational chemistry, ADME, and other key functions

  • Influence the prospective use of computational methods and leverage automated synthesis and high-throughput experimentati

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