Principal Product Manager

Principal Product Manager

Position Summary

Natera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. As we scale our life-saving diagnostics, we are fundamentally transforming how software products are conceived, built, and delivered across our clinical and genomic portfolio.

We are seeking an experienced Principal Digital Product Manager to join our Oncology Comprehensive Genomic Profiling (CGP) Product Engineering team. In this senior individual contributor role, you will serve as the product lead for our most complex platform initiatives — owning end-to-end product strategy and execution across a sophisticated system of interconnected software products.

You will act as the product backbone for our most critical "Pillar" projects. Success in this role demands mastery from three dimensions: partnership with commercial teams to define product strategy/roadmap based on market needs; deep fluency in how end users - lab operations, clinical teams, customer success teams - actually work; and close collaboration with Engineering, R&D, and PMO on product design and delivery. You will synthesize all three into product decisions that hold up end-to-end — from order ingestion through lab execution to patient reporting — ultimately delivering reliable, high-quality solutions t