Senior Product Manager, Oncology
Remote | Bay Area, CA or Austin, TX - Must be located near a Natera laboratory with the ability to commute onsite a few times per month.
Senior Product Manager, Oncology
About the Role: The Senior Product Manager, Oncology leads product development and commercial scale for Signatera, Natera's market-leading tumor-informed minimal residual disease (MRD) assay. This role owns laboratory turnaround time, throughput, and process stability across core lab sites. You will drive the change control review (CCR) pipeline end-to-end from root-cause investigation through requirements authorship, core team leadership, and post-launch hypercare monitoring.
As the product lead for lab process performance, you will leverage operational and sequencing data, build capacity and financial models for equipment and automation investments, and serve as the subject matter expert to Software Engineering and Digital Product Management on instrument integration and LIMS requirements. This is an analytical, data-first, execution-heavy role for someone who bridges technical change control, product requirements, SQL queries, and lab floor operations.
Primary Responsibilities:
- Own and execute the product roadmap for future Si
