Supervisor, RUO Plasma Processing

POSITION SUMMARY: 

Join Natera’s Oncology Research Use Only (RUO) team as a Supervisor for the Signatera Plasma Team. You will direct laboratory staff executing cell-free DNA (cfDNA) extraction, library preparation, and Next-Generation Sequencing (NGS) workflows to advance our personalized Minimal Residual Disease (MRD) assays. Every sample represents a real person, and you will ensure that all lab processes operate with the pace and precision required to support our clinical pipeline.

PRIMARY RESPONSIBILITIES: 

• Oversee the daily scheduling of employees executing DNA extractions, library preparation, Nucleic Acid Quality Control (QC), and NGS workflows
• Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and guide career development
• Take ownership of daily lab operations by directly executing sample processing alongside the team to maintain throughput
• Serve as the primary technical point of contact, using data to guide team members on data interpretation, next steps, and troubleshooting
• Execute process development and method/instrument testing to increase operational precision and scale
• Use data to identify lab process deviations, root-cause the underlying i