Company info

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat aging by reprogramming the epigenome, a new therapeutic mechanism to restore youthful function in aged cells. We’ve built the world’s leading experimental and artificial intelligence system to discover reprogramming medicines at massive scale. Our first products are focused on restoring youthful metabolic, endothelial, and immune function.

Description

NewLimit is seeking a Lipid Chemist to design, synthesize, and characterize ionizable lipids, PEG-lipid Conjugates, peptide and antibody conjugates to build our targeting LNP platform with a particular focus on getting nucleic acid payloads into target cells and tissues beyond the liver.

This is a hands-on bench role with real lipid design ownership. You will work closely with the Delivery Sciences and biology teams to design and build relevant Ionizable and targeting lipids portfolio for New Limit’s pipeline programs.

 

What you’ll do

• Design new ionizable lipids and lipid conjugates for antibodies, peptides, and other targeting moieties across multiple structural families, pushing the platform beyond current-generation materials.
• Devise and execute practical synthetic routes to priori