Executive Director / Vice President, Biology & Translational Pharmacology
Profluent is the frontier AI lab for biology. Profluent builds powerful foundation models for all of life's molecules, unlocking solutions that transform medicine, agriculture, and beyond. Founded in 2022 and headquartered in Emeryville, CA, Profluent is backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures and has raised over $150M to date.
Profluent is seeking an exceptional Executive Director / Vice President, Biology & Translational Pharmacology to lead the scientific strategy and execution of our gene editing therapeutic portfolio. You will help realize the full potential of Profluent’s AI-designed, customized base editors by advancing a defined initial pipeline of genetic medicines for severe inborn metabolic diseases.
Our initial therapeutic focus for this role is liver-directed customized base editing, with future opportunities to expand into additional tissues and therapeutic areas as Profluent’s platform and portfolio grow. You will bring deep expertise in liver biology, metabolic disease, pharmacology, and in vivo disease models, along with the strategic range to help extend Profluent’s therapeutic engine beyond liver over time.
You will directly oversee translational biology and in vivo pharmacology, while also serving as t
