Senior Scientist, Cell Therapy Islet
About the role
Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge the status quo, and who lead with the desire to work on novel ideas. You will join the Beta Islet Team at the Cambridge location to optimize 3D expansion and differentiation in stem cell (SC)-islet differentiation. As a Senior Scientist, you will execute optimization experiments critical to scaling up our differentiation process. The ideal candidate should have ample experience handling bioreactors and performing directed PSC differentiation in 3D. The ability to work in a highly collaborative environment and learn from each other will be essential to your success.
What you’ll do
- Execute routine 2D and 3D PSC expansion, passaging and directed SC-islet differentiation
- Design optimization experiments with the goal to achieve a highly scalable and robust 3D SC-islet differentiation process that is compliant to manufacturing standards
- Optimize the differentiation protocol to achieve highly pure on-target populations
- Hands-on experience with closed systems (tube welder, sealer, single-use assemblies)
- Expertise in controlled bioreactor setup, operation, automation, and process control (DO, p
