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Posted 3h ago•South San Francisco, California, United States

Principal Scientist, Protein Engineering

principalOn-site (San Francisco)Salary undisclosed
Job Description

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

About the Role

As a member of the Protein Engineering team at Xaira, you will play a critical role in the AI-driven discovery and development of protein therapeutics, integrating experimental protein engineering with computational design.

As a Principal Scientist, you will provide scientific and technical leadership from program conception through early discovery and lead optimization. You will partner closely with computational protein designers to guide AI-driven design campaigns and develop experimental strategies to evaluate designed molecules. You will engineer, produce, and characterize therapeutic proteins and anti

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