Senior Scientist I, Computational Protein Design

The Role: 

Generate is seeking a creative and rigorous scientist to develop computational technologies and lead applied platform research that expand what protein therapeutics can do. You will develop reusable methods, scoring and evaluation tools, model benchmarks, agentic systems, and scientific workflows for protein design, engineering, and optimization. Your work will span creating new proteins, modifying existing molecules, and integrating molecular components to unlock new therapeutic applications.

At Generate, model development, protein design, high-throughput experimentation, structural characterization, and therapeutic development operate within one organization. This role offers the opportunity not only to advance computational methods, but to see them shape what proteins are built and tested, learn from rich in-house experimental data, and contribute to medicines in our pipeline. We are looking for someone who is motivated by both technical innovation and its application to drug development.

This role combines technology development with applied platform research. You will identify recurring scientific needs, lead research efforts, and turn successful approaches into durable capabilities with clear interfaces and validated performance. Working with program teams, biologists, and experimental scientists, you will test and refine these capabilities in relevant biol